MolNFT v1 · #142991 · protein
Structure of F. tularensis mgla-sspa solved in the presence of polyp
6ALX · Stringent starvation protein a: “Structure of F. tularensis mgla-sspa solved in the presence of polyp”. X-ray diffraction, 10 pockets (best druggability 0.81). MolNFT v1 #142991 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 6ALX
- Type
- protein
- Length
- 796 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Stringent starvation protein a; Macrophage growth locus a
- UniProt
- A0A0E2ZL39, A0A0E2ZLH6
- Pockets
- 10 · best druggability 0.81
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C, B | Stringent starvation protein a | protein | 195 | 52% helix, 10% strand | A0A0E2ZL39 |
| A, D | Macrophage growth locus a | protein | 203 | 60% helix, 7% strand | A0A0E2ZLH6 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1156 | 0.81 | 0.82 | 115 | empty |
| 2 | 389 | 0.78 | 0.86 | 36 | empty |
| 3 | 372 | 0.73 | 0.83 | 29 | empty |
| 4 | 305 | 0.65 | 0.81 | 39 | empty |
| 5 | 141 | 0.62 | 0.85 | 28 | empty |
Interfaces
4 interfaces between chains.
- C–A · 958 Ų buried · 14 hydrogen bonds · protein-protein
- B–D · 956 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 522 Ų buried · 4 hydrogen bonds · protein-protein
- A–B · 496 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 6ALX · Structure of F. tularensis MglA-SspA solved in the presence of polyP · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0E2ZL39
- Every structure of UniProt A0A0E2ZLH6
- Elsewhere: RCSB PDB 6ALX · PDBe 6ALX · UniProt A0A0E2ZL39 · UniProt A0A0E2ZLH6
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