MolNFT v1 · #14298 · protein
Thermophilic B-1,4-xylanase from nonomuraea flexuosa
1M4W · Endoxylanase: “Thermophilic B-1,4-xylanase from nonomuraea flexuosa”. X-ray diffraction, 3 ligands (NAG, BMA, MAN), 1 pocket (best druggability 0.50). MolNFT v1 #14298 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1M4W
- Type
- protein
- Length
- 197 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoxylanase
- EC
- 3.2.1.8
- Ligands
- NAG, BMA, MAN
- Pockets
- 1 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 5% helix, 61% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoxylanase (EC 3.2.1.8) | protein | 197 | 5% helix, 61% strand | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- BMA · beta-D-mannopyranose · sugar
- MAN · alpha-D-mannopyranose · sugar · chains A
- ACT · Acetate ion · additive · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 168 | 0.50 | 0.78 | 33 | GOL |
Modifications
Observed in the structure: 1 glycan (N-glycosylation).
Compared structures
- 1M4W · Thermophilic b-1,4-xylanase from Nonomuraea flexuosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1M4W · PDBe 1M4W
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