MolNFT v1 · #142849 · protein

Crystal structure of KAP114P

6AHO · Importin subunit beta-5: “Crystal structure of KAP114P”. X-ray diffraction, 9 pockets (best druggability 0.64). MolNFT v1 #142849 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6AHO
Type: protein
Length: 916 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin subunit beta-5
UniProt: P53067
Pockets: 9 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Importin subunit beta-5	protein	916	74% helix, 2% strand	P53067

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	145	0.64	0.86	27	empty
2	230	0.54	0.77	35	empty
3	137	0.45	0.77	20	empty
4	86	0.45	0.80	18	empty
5	65	0.43	0.81	15	empty

Compared structures

6AHO · Crystal structure of Kap114p · the same entry in another collection · chain A against A, TM-score 1.00
P53067 · AlphaFold monomer V2.0 prediction for importin subunit beta-5 (P53067) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P53067
Elsewhere: RCSB PDB 6AHO · PDBe 6AHO · UniProt P53067

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