MolNFT v1 · #142826 · protein
Structural insights for non-natural cofactor binding by the L310R/Q401C mutant of malic enzyme from escherichia COLI
6AGS · NAD-dependent malic enzyme: “Structural insights for non-natural cofactor binding by the L310R/Q401C mutant of malic enzyme from…”. X-ray diffraction, 7 pockets (best druggability 0.79). MolNFT v1 #142826 on GenesisL1: 3D structure…
- PDB
- 6AGS
- Type
- protein
- Length
- 557 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NAD-dependent malic enzyme
- EC
- 1.1.1.38
- UniProt
- A0A1X7B3B3
- Pockets
- 7 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 48% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NAD-dependent malic enzyme (EC 1.1.1.38) | protein | 557 | 48% helix, 11% strand | A0A1X7B3B3 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 974 | 0.79 | 0.81 | 77 | empty |
| 2 | 125 | 0.79 | 0.97 | 27 | empty |
| 3 | 457 | 0.69 | 0.80 | 50 | empty |
| 4 | 87 | 0.53 | 0.84 | 20 | empty |
| 5 | 86 | 0.35 | 0.75 | 18 | empty |
Compared structures
- 6AGS · Structural insights for non-natural cofactor binding by the L310R/Q401C mutant of malic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1X7B3B3
- Elsewhere: RCSB PDB 6AGS · PDBe 6AGS · UniProt A0A1X7B3B3
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