MolNFT v1 · #142790 · protein
Crystal structure of class a B-lactamase, penl, variant CYS69TYR, from burkholderia thailandensis
6AFM · Beta-lactamase: “Crystal structure of class a B-lactamase, penl, variant CYS69TYR, from burkholderia thailandensis”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #142790 on GenesisL1: 3D structure, binding sites…
- PDB
- 6AFM
- Type
- protein
- Length
- 268 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-lactamase
- EC
- 3.5.2.6
- UniProt
- A0A2Z4SUB5
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-lactamase (EC 3.5.2.6) | protein | 268 | 46% helix, 17% strand | A0A2Z4SUB5 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.39 | 0.79 | 21 | empty |
| 2 | 72 | 0.36 | 0.77 | 20 | empty |
Compared structures
- 6AFM · Crystal structure of class A b-lactamase, PenL, variant Cys69Tyr, from Burkholderia… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2Z4SUB5
- Elsewhere: RCSB PDB 6AFM · PDBe 6AFM · UniProt A0A2Z4SUB5
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