MolNFT v1 · #142609 · protein
The crystal structure of vaccinia virus A26 (residues 1-397)
6A9S · Protein A26: “The crystal structure of vaccinia virus A26 (residues 1-397)”. X-ray diffraction, 3 pockets (best druggability 0.34). MolNFT v1 #142609 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6A9S
- Type
- protein
- Length
- 352 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein A26
- UniProt
- P24758
- Pockets
- 3 · best druggability 0.34
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein A26 | protein | 352 | 44% helix, 13% strand | P24758 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 8 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.34 | 0.76 | 20 | EDO |
| 2 | 54 | 0.26 | 0.73 | 15 | empty |
| 3 | 56 | 0.25 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 10 modified, 1 disulfide (engineered, disulfide).
Compared structures
- 6A9S · The crystal structure of vaccinia virus A26 (residues 1-397) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24758
- Elsewhere: RCSB PDB 6A9S · PDBe 6A9S · UniProt P24758
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.