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MolNFT v1 · #142574 · protein

N-terminal domain of fact complex subunit SPT16 from eremothecium gossypii (ashbya gossypii)

6A8M: “N-terminal domain of fact complex subunit SPT16 from eremothecium gossypii (ashbya gossypii)”. X-ray diffraction, 4 pockets (best druggability 0.65). MolNFT v1 #142574 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6A8M
Type
protein
Length
442 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Fact complex subunit SPT16
UniProt
Q756A7
Pockets
4 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AFact complex subunit SPT16protein44242% helix, 22% strandQ756A7

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12350.650.8337empty
2770.510.8421empty
31110.480.8016empty
41160.380.7520empty

Compared structures

  • 6A8M · N-terminal domain of FACT complex subunit SPT16 from Eremothecium gossypii (Ashbya… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q756A7 · AlphaFold monomer V2.0 prediction for fact complex subunit SPT16 (Q756A7) · a predicted model of the same protein · chain A against A, TM-score 0.99

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