MolNFT v1 · #14255 · protein
Solution structure of the catalytic domain of MAPK phosphatase pac-1: insights into substrate-induced enzymatic activation
1M3G · Dual specificity protein phosphatase 2: “Solution structure of the catalytic domain of MAPK phosphatase pac-1: insights into substrate-induced…”. Solution nmr, 1 pocket (best druggability 0.57). MolNFT v1 #14255 on GenesisL1: 3D…
- PDB
- 1M3G
- Type
- protein
- Length
- 145 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dual specificity protein phosphatase 2
- EC
- 3.1.3.48, 3.1.3.16
- UniProt
- Q05923
- Pockets
- 1 · best druggability 0.57
Structure
solution nmr · 1 distinct chain · 39% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity protein phosphatase 2 (EC 3.1.3.48, 3.1.3.16) | protein | 145 | 39% helix, 14% strand | Q05923 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 257 | 0.57 | 0.78 | 31 | empty |
Compared structures
- 1M3G · Solution structure of the catalytic domain of MAPK phosphatase pac-1: insights into… · the same entry in another collection · chain A against A, TM-score 1.00
- Q05923 · AlphaFold monomer V2.0 prediction for dual specificity protein phosphatase 2 (Q05923) · a predicted model of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q05923
- Elsewhere: RCSB PDB 1M3G · PDBe 1M3G · UniProt Q05923
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