MolNFT v1 · #142544 · protein
CYP154C4 from streptomyces sp. W2061
6A7I · Cytochrome P450: “CYP154C4 from streptomyces sp. W2061”. X-ray diffraction, 1 ligand (HEM), 4 pockets (best druggability 0.86). MolNFT v1 #142544 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6A7I
- Type
- protein
- Length
- 409 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome P450
- UniProt
- A0A087KD84
- Ligands
- HEM
- Pockets
- 4 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome P450 | protein | 409 | 51% helix, 11% strand | A0A087KD84 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 676 | 0.86 | 0.90 | 72 | HEM |
| 2 | 81 | 0.58 | 0.87 | 18 | empty |
| 3 | 102 | 0.40 | 0.77 | 20 | empty |
| 4 | 54 | 0.34 | 0.78 | 16 | empty |
Compared structures
- 6A7I · CYP154C4 from Streptomyces sp. W2061 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A087KD84
- Elsewhere: RCSB PDB 6A7I · PDBe 6A7I · UniProt A0A087KD84
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