MolNFT v1 · #142460 · protein

Novel regulators chep and cheq specifically control chemotaxis core gene chevaw transcription in bacterial pathogen campylobacter jejuni

6A51: “Novel regulators chep and cheq specifically control chemotaxis core gene chevaw transcription in bacterial…”. X-ray diffraction, 3 pockets (best druggability 0.59). MolNFT v1 #142460 on GenesisL1: 3D structure, binding sites and…

PDB: 6A51
Type: protein
Length: 315 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cheq
UniProt: A0A0E1ERD4
Pockets: 3 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cheq	protein	157	32% helix, 24% strand	A0A0E1ERD4
B	Cheq	protein	158	33% helix, 27% strand	A0A0E1ERD4

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	323	0.59	0.77	45	empty
2	117	0.46	0.79	18	empty
3	104	0.40	0.76	27	empty

Interfaces

1 interface between chains.

A–B · 1028 Å² buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

6A51 · Novel Regulators CheP and CheQ Specifically Control Chemotaxis Core Gene cheVAW… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0E1ERD4
Elsewhere: RCSB PDB 6A51 · PDBe 6A51 · UniProt A0A0E1ERD4

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