MolNFT v1 · #142220 · protein

Crystal structure of fibronectin-binding protein apa mutant from mycobacterium tuberculosis

5ZXA · Alanine and proline-rich secreted protein apa: “Crystal structure of fibronectin-binding protein apa mutant from mycobacterium tuberculosis”. X-ray diffraction, 1 ligand (HG), 1 pocket (best druggability 0.40). MolNFT v1 #142220 on…

PDB: 5ZXA
Type: protein
Length: 161 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alanine and proline-rich secreted protein apa
UniProt: P9WIR7
Ligands: HG
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alanine and proline-rich secreted protein apa	protein	161	19% helix, 43% strand	P9WIR7

Ligands and binding sites

HG · Mercury (II) ion · metal · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	89	0.40	0.77	16	empty

Compared structures

5ZXA · Crystal structure of fibronectin-binding protein Apa mutant from Mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00
P9WIR7 · AlphaFold monomer V2.0 prediction for alanine and proline-rich secreted protein apa… · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P9WIR7
Elsewhere: RCSB PDB 5ZXA · PDBe 5ZXA · UniProt P9WIR7

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