MolNFT v1 · #142132 · protein

Crystal structure of MERS-cov macro domain in complex with NAD

5ZUB · ORF1A: “Crystal structure of MERS-cov macro domain in complex with NAD”. X-ray diffraction, 1 ligand (NAD), 1 pocket (best druggability 0.53). MolNFT v1 #142132 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5ZUB
Type: protein
Length: 165 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ORF1A
UniProt: T2B9G2
Ligands: NAD
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ORF1A	protein	165	41% helix, 21% strand	T2B9G2

Ligands and binding sites

NAD · Nicotinamide-adenine-dinucleotide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	198	0.53	0.78	31	NAD

Compared structures

5ZUB · Crystal structure of MERS-CoV macro domain in complex with NAD · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt T2B9G2
Elsewhere: RCSB PDB 5ZUB · PDBe 5ZUB · UniProt T2B9G2

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