MolNFT v1 · #142093 · protein

RBM10-RRM2 domain and its lung cancer related mutant

5ZSY · RNA-binding protein 10: “RBM10-RRM2 domain and its lung cancer related mutant”. Solution nmr, 1 pocket (best druggability 0.64). MolNFT v1 #142093 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5ZSY
Type: protein
Length: 88 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-binding protein 10
UniProt: P98175
Pockets: 1 · best druggability 0.64

Structure

solution nmr · 1 distinct chain · 18% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA-binding protein 10	protein	88	18% helix, 22% strand	P98175

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	119	0.64	0.87	25	empty

Compared structures

5ZSY · RBM10-RRM2 domain and its lung cancer related mutant · the same entry in another collection · chain A against A, TM-score 1.00
P98175 · AlphaFold monomer V2.0 prediction for RNA-binding protein 10 (P98175) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P98175
Elsewhere: RCSB PDB 5ZSY · PDBe 5ZSY · UniProt P98175

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