MolNFT v1 · #141937 · protein
Crystal structure of mouse nectin-like molecule 4 (mnecl-4) full ectodomain (IG1-IG3), 2.2A
5ZO1 · Cell adhesion molecule 4: “Crystal structure of mouse nectin-like molecule 4 (mnecl-4) full ectodomain (IG1-IG3), 2.2A”. X-ray diffraction, 2 ligands (NAG, FUC), 1 pocket (best druggability 0.37). MolNFT v1 #141937 on GenesisL1: 3D…
- PDB
- 5ZO1
- Type
- protein
- Length
- 288 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell adhesion molecule 4
- UniProt
- Q8R464
- Ligands
- NAG, FUC
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell adhesion molecule 4 | protein | 288 | 3% helix, 56% strand | Q8R464 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- FUC · alpha-L-fucopyranose · sugar · chains A
- GOL · Glycerol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.37 | 0.77 | 18 | empty |
Modifications
Observed in the structure: 3 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 5ZO1 · Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain (Ig1-Ig3)… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8R464 · AlphaFold monomer V2.0 prediction for cell adhesion molecule 4 (Q8R464) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R464
- Elsewhere: RCSB PDB 5ZO1 · PDBe 5ZO1 · UniProt Q8R464
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.