MolNFT v1 · #14193 · protein
Crystal structure of aquifex aeolicus N-utilization substance G (nusg), space group P2(1)
1M1G · Transcription antitermination protein nusg: “Crystal structure of aquifex aeolicus N-utilization substance G (nusg), space group P2(1)”. X-ray diffraction, 6 pockets (best druggability 0.40). MolNFT v1 #14193 on GenesisL1: 3D…
- PDB
- 1M1G
- Type
- protein
- Length
- 965 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription antitermination protein nusg
- UniProt
- O67757
- Pockets
- 6 · best druggability 0.40
Structure
x-ray diffraction · 4 distinct chains · 17% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription antitermination protein nusg | protein | 240 | 17% helix, 44% strand | O67757 |
| B | Transcription antitermination protein nusg | protein | 242 | 16% helix, 40% strand | O67757 |
| C | Transcription antitermination protein nusg | protein | 244 | 18% helix, 42% strand | O67757 |
| D | Transcription antitermination protein nusg | protein | 239 | 18% helix, 41% strand | O67757 |
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 125 | 0.40 | 0.74 | 22 | empty |
| 2 | 103 | 0.39 | 0.75 | 25 | empty |
| 3 | 78 | 0.33 | 0.75 | 19 | empty |
| 4 | 57 | 0.33 | 0.76 | 10 | empty |
| 5 | 59 | 0.30 | 0.74 | 13 | empty |
Interfaces
4 interfaces between chains.
- B–C · 327 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 66 Ų buried · 0 hydrogen bonds · protein-protein
- A–B · 65 Ų buried · 0 hydrogen bonds · protein-protein
- C–D · 49 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 1M1G · Crystal Structure of Aquifex aeolicus N-utilization substance G (NusG), Space Group P2(1) · the same entry in another collection · chain D against D, TM-score 1.00
- O67757 · AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein… · a predicted model of the same protein · chain D against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67757
- Elsewhere: RCSB PDB 1M1G · PDBe 1M1G · UniProt O67757
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.