MolNFT v1 · #141858 · protein
Human duodenal cytochrome B (dcytb) in substrate free form
5ZLE · Cytochrome B reductase 1: “Human duodenal cytochrome B (dcytb) in substrate free form”. X-ray diffraction, 1 ligand (HEM), 2 pockets (best druggability 0.78). MolNFT v1 #141858 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 5ZLE
- Type
- protein
- Length
- 225 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome B reductase 1
- EC
- 1.-.-.-
- UniProt
- Q53TN4
- Ligands
- HEM
- Pockets
- 2 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 80% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytochrome B reductase 1 (EC 1.-.-.-) | protein | 225 | 80% helix, 1% strand | Q53TN4 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.78 | 0.89 | 39 | HEM |
| 2 | 296 | 0.73 | 0.86 | 30 | HEM |
Compared structures
- 5ZLE · Human duodenal cytochrome b (Dcytb) in substrate free form · the same entry in another collection · chain A against A, TM-score 1.00
- Q53TN4 · AlphaFold monomer V2.0 prediction for plasma membrane ascorbate- dependent reductase… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53TN4
- Elsewhere: RCSB PDB 5ZLE · PDBe 5ZLE · UniProt Q53TN4
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