MolNFT v1 · #141828 · protein
Crystal structure of N-terminal domain of plasmodium vivax P43 in space group P212121
5ZKE · Aminoacyl tRNA synthetase complex-interacting…: “Crystal structure of N-terminal domain of plasmodium vivax P43 in space group P212121”. X-ray diffraction, 5 pockets (best druggability 0.63). MolNFT v1 #141828 on GenesisL1: 3D…
- PDB
- 5ZKE
- Type
- protein
- Length
- 353 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43
- UniProt
- A0A1G4HHT8
- Pockets
- 5 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43 | protein | 179 | 56% helix, 9% strand | A0A1G4HHT8 |
| A | Aminoacyl tRNA synthetase complex-interacting multifunctional protein P43 | protein | 174 | 56% helix, 10% strand | A0A1G4HHT8 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.63 | 0.81 | 36 | empty |
| 2 | 84 | 0.50 | 0.83 | 15 | empty |
| 3 | 123 | 0.47 | 0.78 | 17 | empty |
| 4 | 66 | 0.36 | 0.77 | 14 | empty |
| 5 | 67 | 0.29 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- B–A · 964 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (alkylation).
Compared structures
- 5ZKE · Crystal Structure of N-terminal Domain of Plasmodium vivax p43 in space group P212121 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1G4HHT8
- Elsewhere: RCSB PDB 5ZKE · PDBe 5ZKE · UniProt A0A1G4HHT8
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