MolNFT v1 · #141518 · protein
Structure of a C-terminal S. mutans response regulator vicr domain
5ZA3 · DNA-binding response regulator: “Structure of a C-terminal S. mutans response regulator vicr domain”. X-ray diffraction, 2 pockets (best druggability 0.57). MolNFT v1 #141518 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5ZA3
- Type
- protein
- Length
- 201 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA-binding response regulator
- UniProt
- Q93MY4
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-binding response regulator | protein | 101 | 37% helix, 23% strand | Q93MY4 |
| B | DNA-binding response regulator | protein | 100 | 37% helix, 23% strand | Q93MY4 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 148 | 0.57 | 0.82 | 21 | empty |
| 2 | 146 | 0.55 | 0.81 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 319 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5ZA3 · Structure of a C-terminal S. mutans response regulator VicR domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q93MY4
- Elsewhere: RCSB PDB 5ZA3 · PDBe 5ZA3 · UniProt Q93MY4
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