MolNFT v1 · #141515 · protein
A cryo-protectant induces the conformational change of glyceraldehyde- 3-phosphate dehydrogenase
5ZA0 · Glyceraldehyde-3-phosphate dehydrogenase a: “A cryo-protectant induces the conformational change of glyceraldehyde- 3-phosphate dehydrogenase”. X-ray diffraction, 2 ligands (GLC, SO4), 2 pockets (best druggability 0.59). MolNFT v1…
- PDB
- 5ZA0
- Type
- protein
- Length
- 330 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glyceraldehyde-3-phosphate dehydrogenase a
- EC
- 1.2.1.12
- UniProt
- P0A9B2
- Ligands
- GLC, SO4
- Pockets
- 2 · best druggability 0.59
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glyceraldehyde-3-phosphate dehydrogenase a (EC 1.2.1.12) | protein | 330 | 31% helix, 28% strand | P0A9B2 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 396 | 0.59 | 0.76 | 34 | empty |
| 2 | 57 | 0.29 | 0.74 | 13 | empty |
Compared structures
- 5ZA0 · A cryo-protectant induces the conformational change of glyceraldehyde-3-phosphate… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A9B2 · AlphaFold monomer V2.0 prediction for glyceraldehyde-3-phosphate dehydrogenase a (P0A9B2) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A9B2
- Elsewhere: RCSB PDB 5ZA0 · PDBe 5ZA0 · UniProt P0A9B2
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