MolNFT v1 · #141492 · protein
Crystal structure of chorismate synthase from pseudomonas aeruginosa
5Z9A: “Crystal structure of chorismate synthase from pseudomonas aeruginosa”. X-ray diffraction, 8 pockets (best druggability 0.65). MolNFT v1 #141492 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5Z9A
- Type
- protein
- Length
- 497 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chorismate synthase
- EC
- 4.2.3.5
- UniProt
- B7UV40
- Pockets
- 8 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chorismate synthase (EC 4.2.3.5) | protein | 247 | 32% helix, 26% strand | B7UV40 |
| B | Chorismate synthase (EC 4.2.3.5) | protein | 250 | 32% helix, 27% strand | B7UV40 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 422 | 0.65 | 0.78 | 49 | empty |
| 2 | 349 | 0.61 | 0.78 | 37 | empty |
| 3 | 126 | 0.49 | 0.80 | 21 | empty |
| 4 | 69 | 0.47 | 0.83 | 22 | empty |
| 5 | 87 | 0.44 | 0.80 | 25 | empty |
Interfaces
1 interface between chains.
- A–B · 2185 Ų buried · 39 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7UV40
- Elsewhere: RCSB PDB 5Z9A · PDBe 5Z9A · UniProt B7UV40
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