MolNFT v1 · #141487 · protein

Structural basis for specific inhibition of highly sensitive SHHTL7 receptor

5Z95 · Hyposensitive to light 7: “Structural basis for specific inhibition of highly sensitive SHHTL7 receptor”. X-ray diffraction, 2 ligands (EGC, SO4), 1 pocket (best druggability 0.77). MolNFT v1 #141487 on GenesisL1: 3D structure…

PDB: 5Z95
Type: protein
Length: 268 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hyposensitive to light 7
UniProt: A0A0M3PNA2
Ligands: EGC, SO4
Pockets: 1 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hyposensitive to light 7	protein	268	46% helix, 17% strand	A0A0M3PNA2

Ligands and binding sites

EGC · 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-tetramethyl-butyl)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol · ligand · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	288	0.77	0.88	31	EGC

Compared structures

5Z95 · Structural basis for specific inhibition of highly sensitive ShHTL7 receptor · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0M3PNA2
Elsewhere: RCSB PDB 5Z95 · PDBe 5Z95 · UniProt A0A0M3PNA2

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.