MolNFT v1 · #141449 · protein
Crystal structure of striga hermonthica HTL1 (SHHTL1)
5Z7W · Hyposensitive to light 1: “Crystal structure of striga hermonthica HTL1 (SHHTL1)”. X-ray diffraction, 2 ligands (MG, NA), 3 pockets (best druggability 0.66). MolNFT v1 #141449 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5Z7W
- Type
- protein
- Length
- 540 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hyposensitive to light 1
- UniProt
- A0A0M4AV81
- Ligands
- MG, NA
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hyposensitive to light 1 | protein | 269 | 47% helix, 18% strand | A0A0M4AV81 |
| B | Hyposensitive to light 1 | protein | 271 | 46% helix, 18% strand | A0A0M4AV81 |
Ligands and binding sites
- MG · Magnesium ion · metal · 3 copies · chains A, B
- NA · Sodium ion · metal · 3 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.66 | 0.89 | 23 | MG, GOL |
| 2 | 75 | 0.64 | 0.90 | 20 | GOL |
| 3 | 225 | 0.51 | 0.76 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 667 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 5Z7W · Crystal structure of Striga hermonthica HTL1 (ShHTL1) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0M4AV81
- Elsewhere: RCSB PDB 5Z7W · PDBe 5Z7W · UniProt A0A0M4AV81
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