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MolNFT v1 · #141398 · protein

Structure of the recombination mediator protein recf in recfor pathway

5Z67 · DNA replication and repair protein recf: “Structure of the recombination mediator protein recf in recfor pathway”. X-ray diffraction, 4 pockets (best druggability 0.67). MolNFT v1 #141398 on GenesisL1: 3D structure, binding sites…

PDB
5Z67
Type
protein
Length
367 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA replication and repair protein recf
UniProt
Q8RDL3
Pockets
4 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA replication and repair protein recfprotein36746% helix, 23% strandQ8RDL3

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11910.670.8634empty
2850.560.8618empty
31160.410.7515empty
4550.260.7314empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 5Z67 · Structure of the recombination mediator protein RecF in RecFOR pathway · the same entry in another collection · chain A against A, TM-score 1.00
  • Q8RDL3 · AlphaFold monomer V2.0 prediction for DNA replication and repair protein recf (Q8RDL3) · a predicted model of the same protein · chain A against A, TM-score 0.98

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