MolNFT v1 · #141049 · protein

Crystal structure of the Fab fragment of fviia antibody MAB4F5

5YUP · The heavy chain of the Fab fragment of fviia antibody MAB4F5: “Crystal structure of the Fab fragment of fviia antibody MAB4F5”. X-ray diffraction, 5 pockets (best druggability 0.60). MolNFT v1 #141049 on GenesisL1: 3D structure…

PDB: 5YUP
Type: protein
Length: 434 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: The heavy chain of the Fab fragment of fviia antibody MAB4F5; The light chain of the Fab…
Pockets: 5 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains · 8% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
H	The heavy chain of the Fab fragment of fviia antibody MAB4F5	protein	219	10% helix, 51% strand	—
L	The light chain of the Fab fragment of fviia antibody MAB4F5	protein	215	6% helix, 50% strand	—

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	559	0.60	0.73	59	empty
2	73	0.50	0.85	23	empty
3	185	0.50	0.77	37	empty
4	83	0.35	0.75	20	empty
5	86	0.35	0.75	19	empty

Interfaces

1 interface between chains.

H–L · 1907 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

5YUP · Crystal Structure of the Fab fragment of FVIIa antibody mAb4F5 · the same entry in another collection · chain H against H, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5YUP · PDBe 5YUP

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.