MolNFT v1 · #141032 · protein

Crystal structure of exportin-5

5YU7: “Crystal structure of exportin-5”. X-ray diffraction, 15 pockets (best druggability 0.72). MolNFT v1 #141032 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5YU7
Type: protein
Length: 1,118 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Exportin-5
UniProt: Q9HAV4
Pockets: 15 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Exportin-5	protein	1118	70% helix, 1% strand	Q9HAV4

Pockets

15 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	758	0.72	0.78	56	empty
2	256	0.54	0.76	26	empty
3	106	0.51	0.82	23	empty
4	186	0.47	0.75	25	empty
5	170	0.42	0.73	27	empty

Compared structures

5YU7 · Crystal structure of exportin-5 · the same entry in another collection · chain A against A, TM-score 1.00
Q9HAV4 · AlphaFold monomer V2.0 prediction for exportin-5 (Q9HAV4) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HAV4
Elsewhere: RCSB PDB 5YU7 · PDBe 5YU7 · UniProt Q9HAV4

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