MolNFT v1 · #140996 · protein
Structure of the human mitogen-activated protein kinase kinase 1 S218D and S222D mutant
5YT3: “Structure of the human mitogen-activated protein kinase kinase 1 S218D and S222D mutant”. X-ray diffraction, 2 ligands (ANP, MG). MolNFT v1 #140996 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YT3
- Type
- protein
- Length
- 1,205 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q02750
- Ligands
- ANP, MG
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 297 | — | Q02750 |
| B | — | protein | 311 | — | Q02750 |
| C | — | protein | 288 | — | Q02750 |
| D | — | protein | 309 | — | Q02750 |
Ligands and binding sites
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · 4 copies · chains A, B, C, D
- MG · Magnesium ion · metal · 2 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YT3 · Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 S218D and S222D mutant · the same entry in another collection · chain D against D, TM-score 1.00
- Q02750 · AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase… · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02750
- Elsewhere: RCSB PDB 5YT3 · PDBe 5YT3 · UniProt Q02750
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