MolNFT v1 · #140844 · protein
Crystal structure of beta-C25/C30/C35-prene synthase
5YO8 · Tetraprenyl-beta-curcumene synthase: “Crystal structure of beta-C25/C30/C35-prene synthase”. X-ray diffraction, 4 pockets (best druggability 0.81). MolNFT v1 #140844 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YO8
- Type
- protein
- Length
- 695 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetraprenyl-beta-curcumene synthase
- UniProt
- A0A094YZ24
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 2 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetraprenyl-beta-curcumene synthase | protein | 349 | 76% helix, 0% strand | A0A094YZ24 |
| B | Tetraprenyl-beta-curcumene synthase | protein | 346 | 76% helix, 0% strand | A0A094YZ24 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 705 | 0.81 | 0.84 | 62 | empty |
| 2 | 383 | 0.72 | 0.83 | 38 | empty |
| 3 | 242 | 0.68 | 0.84 | 26 | empty |
| 4 | 125 | 0.43 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 993 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 5YO8 · Crystal structure of beta-C25/C30/C35-prene synthase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A094YZ24
- Elsewhere: RCSB PDB 5YO8 · PDBe 5YO8 · UniProt A0A094YZ24
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