MolNFT v1 · #14084 · protein
Structure of phosphotransferase phosphoglucomutase from rabbit
1LXT · Phosphoglucomutase (dephospho form): “Structure of phosphotransferase phosphoglucomutase from rabbit”. X-ray diffraction, 2 ligands (CD, SO4), 16 pockets (best druggability 0.68). MolNFT v1 #14084 on GenesisL1: 3D structure, binding…
- PDB
- 1LXT
- Type
- protein
- Length
- 1,122 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoglucomutase (dephospho form)
- EC
- 5.4.2.2
- UniProt
- P00949
- Ligands
- CD, SO4
- Pockets
- 16 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Phosphoglucomutase (dephospho form) (EC 5.4.2.2) | protein | 561 | 36% helix, 25% strand | P00949 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.68 | 0.78 | 62 | SO4 |
| 2 | 364 | 0.63 | 0.79 | 43 | empty |
| 3 | 384 | 0.62 | 0.78 | 39 | SO4 |
| 4 | 207 | 0.53 | 0.77 | 25 | empty |
| 5 | 179 | 0.49 | 0.77 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 600 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00949
- Elsewhere: RCSB PDB 1LXT · PDBe 1LXT · UniProt P00949
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