MolNFT v1 · #140660 · protein
Structure of lactococcus lactis zitr, C30AH42A mutant
5YI0 · Zinc transport transcriptional regulator: “Structure of lactococcus lactis zitr, C30AH42A mutant”. X-ray diffraction, 1 ligand (ZN), 7 pockets (best druggability 0.54). MolNFT v1 #140660 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5YI0
- Type
- protein
- Length
- 584 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc transport transcriptional regulator
- UniProt
- Q9CDU5
- Ligands
- ZN
- Pockets
- 7 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 59% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A, C, D | Zinc transport transcriptional regulator | protein | 146 | 59% helix, 8% strand | Q9CDU5 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains B, A, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 277 | 0.54 | 0.76 | 33 | empty |
| 2 | 110 | 0.46 | 0.79 | 24 | empty |
| 3 | 55 | 0.45 | 0.85 | 13 | empty |
| 4 | 216 | 0.45 | 0.73 | 30 | empty |
| 5 | 53 | 0.39 | 0.81 | 13 | empty |
Interfaces
4 interfaces between chains.
- A–C · 2185 Ų buried · 8 hydrogen bonds · protein-protein
- A–D · 264 Ų buried · 3 hydrogen bonds · protein-protein
- B–A · 258 Ų buried · 3 hydrogen bonds · protein-protein
- C–D · 162 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5YI0 · Structure of Lactococcus lactis ZitR, C30AH42A mutant · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9CDU5
- Elsewhere: RCSB PDB 5YI0 · PDBe 5YI0 · UniProt Q9CDU5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.