MolNFT v1 · #140584 · protein

Solution structure of human MOG1

5YFG · Ran guanine nucleotide release factor: “Solution structure of human MOG1”. Solution nmr, 3 pockets (best druggability 0.66). MolNFT v1 #140584 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5YFG
Type: protein
Length: 186 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ran guanine nucleotide release factor
UniProt: Q9HD47
Pockets: 3 · best druggability 0.66

Structure

solution nmr · 1 distinct chain · 15% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ran guanine nucleotide release factor	protein	186	15% helix, 32% strand	Q9HD47

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.66	0.93	21	empty
2	93	0.61	0.88	27	empty
3	51	0.37	0.80	19	empty

Compared structures

5YFG · Solution structure of human MOG1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9HD47 · AlphaFold monomer V2.0 prediction for ran guanine nucleotide release factor (Q9HD47) · a predicted model of the same protein · chain A against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HD47
Elsewhere: RCSB PDB 5YFG · PDBe 5YFG · UniProt Q9HD47

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