MolNFT v1 · #140424 · protein
Crystal structure of MARF1 lotus domain from mus musculus
5YAD · Meiosis regulator and mRNA stability factor 1: “Crystal structure of MARF1 lotus domain from mus musculus”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.33). MolNFT v1 #140424 on GenesisL1: 3D structure, binding…
- PDB
- 5YAD
- Type
- protein
- Length
- 144 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Meiosis regulator and mRNA stability factor 1
- UniProt
- Q8BJ34
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Meiosis regulator and mRNA stability factor 1 | protein | 73 | 55% helix, 15% strand | Q8BJ34 |
| B | Meiosis regulator and mRNA stability factor 1 | protein | 71 | 51% helix, 15% strand | Q8BJ34 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.33 | 0.78 | 13 | empty |
| 2 | 62 | 0.32 | 0.76 | 11 | empty |
Interfaces
1 interface between chains.
- A–B · 242 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 5YAD · Crystal structure of Marf1 Lotus domain from Mus musculus · the same entry in another collection · chain A against A, TM-score 1.00
- Q8BJ34 · AlphaFold monomer V2.0 prediction for meiosis regulator and mRNA stability factor 1… · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BJ34
- Elsewhere: RCSB PDB 5YAD · PDBe 5YAD · UniProt Q8BJ34
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