MolNFT v1 · #140423 · protein

Crystal structure of wt TRM5B from pyrococcus abyssi

5YAC · TRNA (GUANINE(37)-N1)-methyltransferase TRM5B: “Crystal structure of wt TRM5B from pyrococcus abyssi”. X-ray diffraction, 1 pocket (best druggability 0.60). MolNFT v1 #140423 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5YAC
Type: protein
Length: 330 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TRNA (GUANINE(37)-N1)-methyltransferase TRM5B
EC: 2.1.1.228
UniProt: Q9V0Q0
Pockets: 1 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TRNA (GUANINE(37)-N1)-methyltransferase TRM5B (EC 2.1.1.228)	protein	330	29% helix, 35% strand	Q9V0Q0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	299	0.60	0.78	48	empty

Compared structures

5YAC · Crystal structure of WT Trm5b from Pyrococcus abyssi · the same entry in another collection · chain A against A, TM-score 1.00
Q9V0Q0 · AlphaFold monomer V2.0 prediction for tRNA (GUANINE(37)-N1)-methyltransferase TRM5B… · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9V0Q0
Elsewhere: RCSB PDB 5YAC · PDBe 5YAC · UniProt Q9V0Q0

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