MolNFT v1 · #140364 · protein
Mycobacterium tuberculosis 3-hydroxyisobutyrate dehydrogenase (mthibadh) + (S)-3-hydroxyisobutyrate (S-hiba)
5Y8I: “Mycobacterium tuberculosis 3-hydroxyisobutyrate dehydrogenase (mthibadh) + (S)-3-hydroxyisobutyrate (S-hiba)”. X-ray diffraction, 2 ligands (9ON, HUI). MolNFT v1 #140364 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5Y8I
- Type
- protein
- Length
- 583 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P9WNY5
- Ligands
- 9ON, HUI
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 292 | — | P9WNY5 |
| B | — | protein | 291 | — | P9WNY5 |
Ligands and binding sites
- 9ON · (2~{S})-2-methylpentanedioic acid · ligand · 2 copies · chains A, B
- HUI · (2S)-2-methyl-3-oxidanyl-propanoic acid · ligand · chains A, B
- GOL · Glycerol · additive · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5Y8I · Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) +… · the same entry in another collection · chain A against A, TM-score 1.00
- P9WNY5 · AlphaFold monomer V2.0 prediction for probable 3-hydroxyisobutyrate dehydrogenase (P9WNY5) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WNY5
- Elsewhere: RCSB PDB 5Y8I · PDBe 5Y8I · UniProt P9WNY5
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