MolNFT v1 · #139962 · protein
Sterol 3-beta-glucosyltransferase (UGT51) from saccharomyces cerevisiae (strain atcc 204508 / S288C)
5XVM: “Sterol 3-beta-glucosyltransferase (UGT51) from saccharomyces cerevisiae (strain atcc 204508 / S288C)”. X-ray diffraction, 7 pockets (best druggability 0.84). MolNFT v1 #139962 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5XVM
- Type
- protein
- Length
- 808 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sterol 3-beta-glucosyltransferase
- EC
- 2.4.1.173
- UniProt
- Q06321
- Pockets
- 7 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 50% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sterol 3-beta-glucosyltransferase (EC 2.4.1.173) | protein | 410 | 50% helix, 14% strand | Q06321 |
| B | Sterol 3-beta-glucosyltransferase (EC 2.4.1.173) | protein | 398 | 51% helix, 13% strand | Q06321 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 851 | 0.84 | 0.86 | 103 | empty |
| 2 | 195 | 0.71 | 0.88 | 24 | empty |
| 3 | 151 | 0.64 | 0.85 | 33 | empty |
| 4 | 126 | 0.58 | 0.84 | 23 | empty |
| 5 | 80 | 0.40 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 894 Ų buried · 13 hydrogen bonds · protein-protein
Compared structures
- 5XVM · Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC… · the same entry in another collection · chain A against A, TM-score 1.00
- Q06321 · AlphaFold monomer V2.0 prediction for sterol 3-beta- glucosyltransferase (Q06321) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06321
- Elsewhere: RCSB PDB 5XVM · PDBe 5XVM · UniProt Q06321
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