MolNFT v1 · #139709 · protein

Structure of CYP106A2 from bacillus sp. pamc 23377

5XNT · Cytochrome P450 CYP106: “Structure of CYP106A2 from bacillus sp. pamc 23377”. X-ray diffraction, 1 ligand (HEM), 4 pockets (best druggability 0.73). MolNFT v1 #139709 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5XNT
Type: protein
Length: 392 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytochrome P450 CYP106
Ligands: HEM
Pockets: 4 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytochrome P450 CYP106	protein	392	52% helix, 12% strand	—

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	599	0.73	0.81	48	HEM
2	148	0.55	0.81	27	empty
3	51	0.29	0.76	13	empty
4	57	0.29	0.75	13	empty

Compared structures

5XNT · Structure of CYP106A2 from Bacillus sp. PAMC 23377 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 5XNT · PDBe 5XNT

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