MolNFT v1 · #139648 · protein
Human N-terminal domain of fact complex subunit SPT16
5XM2: “Human N-terminal domain of fact complex subunit SPT16”. X-ray diffraction, 10 pockets (best druggability 0.68). MolNFT v1 #139648 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5XM2
- Type
- protein
- Length
- 864 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fact complex subunit SPT16
- UniProt
- Q9Y5B9
- Pockets
- 10 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Fact complex subunit SPT16 | protein | 432 | 41% helix, 22% strand | Q9Y5B9 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 418 | 0.68 | 0.80 | 62 | empty |
| 2 | 398 | 0.67 | 0.80 | 62 | empty |
| 3 | 264 | 0.64 | 0.81 | 32 | PEG |
| 4 | 137 | 0.57 | 0.83 | 25 | empty |
| 5 | 126 | 0.52 | 0.81 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 598 Ų buried · 15 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5B9
- Elsewhere: RCSB PDB 5XM2 · PDBe 5XM2 · UniProt Q9Y5B9
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