Crystal structure of plsy (ygih), an integral membrane glycerol 3- phosphate acyltransferase - the acyl phosphate form

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Ligands and binding sites

• 78M · (2S)-2,3-dihydroxypropyl(7z)-pentadec-7-enoate · ligand · 7 copies · chains A
• 87O · phosphono hexadecanoate · ligand · 2 copies · chains A
• K · Potassium ion · metal · 2 copies · chains A
• PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 1 modified (formylation).

Compared structures

• 5XJ7 · Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate… · the same entry in another collection · chain A against A, TM-score 1.00
• O66905 · AlphaFold monomer V2.0 prediction for glycerol-3-phosphate acyltransferase (O66905) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O66905
• Elsewhere: RCSB PDB 5XJ7 · PDBe 5XJ7 · UniProt O66905