MolNFT v1 · #139518 · protein

Structure and function of the tpr domain

5XI8 · Beta-barrel assembly-enhancing protease: “Structure and function of the tpr domain”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #139518 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5XI8
Type: protein
Length: 175 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-barrel assembly-enhancing protease
EC: 3.4.-.-
UniProt: P66948
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-barrel assembly-enhancing protease (EC 3.4.-.-)	protein	175	80% helix, 0% strand	P66948

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	149	0.45	0.76	16	empty

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

5XI8 · Structure and function of the TPR domain · the same entry in another collection · chain A against A, TM-score 1.00
P66948 · AlphaFold monomer V2.0 prediction for beta-barrel assembly-enhancing protease (P66948) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P66948
Elsewhere: RCSB PDB 5XI8 · PDBe 5XI8 · UniProt P66948

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