MolNFT v1 · #139511 · protein
Crystal structure of fabv, a new class of enyl-acyl carrier protein reductase from vibrio fischeri
5XI0 · Enoyl-[acyl-carrier-protein] reductase [NADH]: “Crystal structure of fabv, a new class of enyl-acyl carrier protein reductase from vibrio fischeri”. X-ray diffraction, 9 pockets (best druggability 0.85). MolNFT v1 #139511 on…
- PDB
- 5XI0
- Type
- protein
- Length
- 800 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enoyl-[acyl-carrier-protein] reductase [NADH]
- EC
- 1.3.1.9
- UniProt
- Q5E6G3
- Pockets
- 9 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Enoyl-[acyl-carrier-protein] reductase [NADH] (EC 1.3.1.9) | protein | 400 | 41% helix, 17% strand | Q5E6G3 |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 570 | 0.85 | 0.90 | 72 | empty |
| 2 | 937 | 0.82 | 0.84 | 83 | empty |
| 3 | 163 | 0.72 | 0.90 | 28 | empty |
| 4 | 225 | 0.65 | 0.83 | 28 | empty |
| 5 | 62 | 0.57 | 0.89 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 959 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 5XI0 · Crystal structure of FabV, a new class of enyl-acyl carrier protein reductase from Vibrio… · the same entry in another collection · chain A against A, TM-score 1.00
- Q5E6G3 · AlphaFold monomer V2.0 prediction for enoyl-[acyl-carrier-protein] reductase [NADH]… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5E6G3
- Elsewhere: RCSB PDB 5XI0 · PDBe 5XI0 · UniProt Q5E6G3
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