MolNFT v1 · #139472 · protein

Crystal structure of human WBSCR16

5XGS · RCC1-like G exchanging factor-like protein: “Crystal structure of human WBSCR16”. X-ray diffraction, 4 pockets (best druggability 0.74). MolNFT v1 #139472 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5XGS
Type: protein
Length: 796 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RCC1-like G exchanging factor-like protein
UniProt: Q96I51
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RCC1-like G exchanging factor-like protein	protein	398	3% helix, 43% strand	Q96I51
B	RCC1-like G exchanging factor-like protein	protein	398	3% helix, 43% strand	Q96I51

Pockets

4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.74	0.88	34	empty
2	323	0.73	0.85	50	empty
3	217	0.68	0.85	38	empty
4	394	0.66	0.79	56	empty

Interfaces

1 interface between chains.

A–B · 683 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

5XGS · Crystal structure of human WBSCR16 · the same entry in another collection · chain A against A, TM-score 1.00
Q96I51 · AlphaFold monomer V2.0 prediction for RCC1-like G exchanging factor- like protein (Q96I51) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96I51
Elsewhere: RCSB PDB 5XGS · PDBe 5XGS · UniProt Q96I51

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