MolNFT v1 · #139469 · protein
Structure of sizzled from xenopus laevis at 2.08 ångströms resolution
5XGP · Secreted XWNT8 inhibitor sizzled: “Structure of sizzled from xenopus laevis at 2.08 ångströms resolution”. X-ray diffraction, 2 ligands (CL, SO4), 2 pockets (best druggability 0.41). MolNFT v1 #139469 on GenesisL1: 3D structure…
- PDB
- 5XGP
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Secreted XWNT8 inhibitor sizzled
- UniProt
- O73821
- Ligands
- CL, SO4
- Pockets
- 2 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Secreted XWNT8 inhibitor sizzled | protein | 249 | 35% helix, 20% strand | O73821 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 94 | 0.41 | 0.77 | 21 | empty |
| 2 | 62 | 0.30 | 0.74 | 15 | empty |
Modifications
Observed in the structure: 8 disulfide (disulfide).
Compared structures
- 5XGP · structure of Sizzled from Xenopus laevis at 2.08 angstroms resolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O73821
- Elsewhere: RCSB PDB 5XGP · PDBe 5XGP · UniProt O73821
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