MolNFT v1 · #139456 · protein

Crystal structure of smggds-558

5XGC · RAP1 GTPase-GDP dissociation stimulator 1: “Crystal structure of smggds-558”. X-ray diffraction, 1 pocket (best druggability 0.68). MolNFT v1 #139456 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5XGC
Type: protein
Length: 473 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RAP1 GTPase-GDP dissociation stimulator 1
UniProt: P52306
Pockets: 1 · best druggability 0.68

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RAP1 GTPase-GDP dissociation stimulator 1	protein	473	74% helix, 0% strand	P52306

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	409	0.68	0.81	53	empty

Compared structures

5XGC · Crystal structure of SmgGDS-558 · the same entry in another collection · chain A against A, TM-score 1.00
P52306 · AlphaFold monomer V2.0 prediction for RAP1 GTPase-GDP dissociation stimulator 1 (P52306) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52306
Elsewhere: RCSB PDB 5XGC · PDBe 5XGC · UniProt P52306

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.