MolNFT v1 · #139332 · protein
Crystal structure of VPS29 double mutant (D62A/H86A) from entamoeba histolytica
5XCK · Vacuolar protein sorting-associated protein 29: “Crystal structure of VPS29 double mutant (D62A/H86A) from entamoeba histolytica”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #139332 on GenesisL1: 3D structure…
- PDB
- 5XCK
- Type
- protein
- Length
- 361 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Vacuolar protein sorting-associated protein 29
- UniProt
- Q9BI08
- Pockets
- 1 · best druggability 0.34
Structure
x-ray diffraction · 2 distinct chains · 16% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vacuolar protein sorting-associated protein 29 | protein | 181 | 17% helix, 40% strand | Q9BI08 |
| B | Vacuolar protein sorting-associated protein 29 | protein | 180 | 16% helix, 34% strand | Q9BI08 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 76 | 0.34 | 0.75 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 539 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 5XCK · Crystal structure of Vps29 double mutant (D62A/H86A) from Entamoeba histolytica · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BI08
- Elsewhere: RCSB PDB 5XCK · PDBe 5XCK · UniProt Q9BI08
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