MolNFT v1 · #139315 · protein
Crystal structure of gh family 81 beta-1,3-glucanase from rhizomucr miehei complexed with laminaripentaose
5XBZ · Endo-beta-1,3-glucanase: “Crystal structure of gh family 81 beta-1,3-glucanase from rhizomucr miehei complexed with laminaripentaose”. X-ray diffraction, 1 ligand (BGC), 10 pockets (best druggability 0.73). MolNFT v1 #139315 on…
- PDB
- 5XBZ
- Type
- protein
- Length
- 1,415 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endo-beta-1,3-glucanase
- EC
- 3.2.1.39
- UniProt
- A0A023I7E1
- Ligands
- BGC
- Pockets
- 10 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endo-beta-1,3-glucanase (EC 3.2.1.39) | protein | 710 | 33% helix, 24% strand | A0A023I7E1 |
| B | Endo-beta-1,3-glucanase (EC 3.2.1.39) | protein | 705 | 33% helix, 23% strand | A0A023I7E1 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · 26 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.73 | 1.00 | 19 | empty |
| 2 | 289 | 0.66 | 0.82 | 33 | empty |
| 3 | 245 | 0.65 | 0.83 | 29 | empty |
| 4 | 280 | 0.60 | 0.79 | 37 | BGC |
| 5 | 491 | 0.60 | 0.75 | 55 | empty |
Interfaces
1 interface between chains.
- A–B · 397 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 5XBZ · Crystal structure of GH family 81 beta-1,3-glucanase from Rhizomucr miehei complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A023I7E1
- Elsewhere: RCSB PDB 5XBZ · PDBe 5XBZ · UniProt A0A023I7E1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.