MolNFT v1 · #139281 · protein

Structure of phac from chromobacterium sp. USM2

5XAV · Intracellular polyhydroxyalkanoate synthase: “Structure of phac from chromobacterium sp. USM2”. X-ray diffraction, 5 pockets (best druggability 0.79). MolNFT v1 #139281 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5XAV
Type: protein
Length: 754 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Intracellular polyhydroxyalkanoate synthase
UniProt: E1APK1
Pockets: 5 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 37% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Intracellular polyhydroxyalkanoate synthase	protein	376	37% helix, 19% strand	E1APK1
B	Intracellular polyhydroxyalkanoate synthase	protein	378	38% helix, 19% strand	E1APK1

Pockets

5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	806	0.79	0.82	104	empty
2	95	0.76	0.97	25	empty
3	294	0.63	0.80	47	empty
4	173	0.55	0.80	21	empty
5	187	0.54	0.79	22	empty

Interfaces

1 interface between chains.

A–B · 1195 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

5XAV · Structure of PhaC from Chromobacterium sp. USM2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E1APK1
Elsewhere: RCSB PDB 5XAV · PDBe 5XAV · UniProt E1APK1

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