MolNFT v1 · #139252 · protein

Crystal structure of O-acetylserine sulfhydrylase from planctomyces limnophila

5XA2 · Cysteine synthase: “Crystal structure of O-acetylserine sulfhydrylase from planctomyces limnophila”. X-ray diffraction, 2 pockets (best druggability 0.78). MolNFT v1 #139252 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 5XA2
Type: protein
Length: 618 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cysteine synthase
EC: 2.5.1.47
UniProt: D5STP0
Pockets: 2 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Cysteine synthase (EC 2.5.1.47)	protein	309	44% helix, 18% strand	D5STP0

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1001	0.78	0.80	99	empty
2	78	0.52	0.85	21	empty

Interfaces

1 interface between chains.

A–B · 2406 Å² buried · 34 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (cofactor).

Compared structures

5XA2 · Crystal Structure of O-acetylserine sulfhydrylase from Planctomyces Limnophila · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D5STP0
Elsewhere: RCSB PDB 5XA2 · PDBe 5XA2 · UniProt D5STP0

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