MolNFT v1 · #139181 · protein
Structure of tsrd from streptomyces laurentii
5X7L: “Structure of tsrd from streptomyces laurentii”. X-ray diffraction, 2 pockets (best druggability 0.63). MolNFT v1 #139181 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5X7L
- Type
- protein
- Length
- 269 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tsrd
- UniProt
- C0JRY3
- Pockets
- 2 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tsrd | protein | 134 | 32% helix, 42% strand | C0JRY3 |
| B | Tsrd | protein | 135 | 33% helix, 41% strand | C0JRY3 |
Ligands and binding sites
- IPA · Isopropyl alcohol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 313 | 0.63 | 0.79 | 37 | IPA |
| 2 | 249 | 0.63 | 0.81 | 28 | IPA |
Interfaces
1 interface between chains.
- A–B · 1045 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 5X7L · Structure of TsrD from Streptomyces laurentii · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C0JRY3
- Elsewhere: RCSB PDB 5X7L · PDBe 5X7L · UniProt C0JRY3
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