MolNFT v1 · #139047 · protein
Leukotriene B4 receptor BLT1 in complex with BIIL260
5X33 · LTB4 RECEPTOR,LYSOZYME,LTB4 receptor: “Leukotriene B4 receptor BLT1 in complex with BIIL260”. X-ray diffraction, 1 ligand (7Y9), 3 pockets (best druggability 0.80). MolNFT v1 #139047 on GenesisL1: 3D structure, binding sites and…
- PDB
- 5X33
- Type
- protein
- Length
- 439 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LTB4 RECEPTOR,LYSOZYME,LTB4 receptor
- EC
- 3.2.1.17
- UniProt
- Q9WTK1, A0A097J792
- Ligands
- 7Y9
- Pockets
- 3 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 69% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LTB4 RECEPTOR,LYSOZYME,LTB4 receptor (EC 3.2.1.17) | protein | 439 | 69% helix, 5% strand | Q9WTK1, A0A097J792 |
Ligands and binding sites
- 7Y9 · 4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamid E · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 425 | 0.80 | 0.88 | 47 | 7Y9 |
| 2 | 537 | 0.68 | 0.78 | 54 | empty |
| 3 | 82 | 0.33 | 0.74 | 18 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 5X33 · Leukotriene B4 receptor BLT1 in complex with BIIL260 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WTK1
- Every structure of UniProt A0A097J792
- Elsewhere: RCSB PDB 5X33 · PDBe 5X33 · UniProt Q9WTK1 · UniProt A0A097J792
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.