MolNFT v1 · #138960 · protein
Free serine kinase (E30A mutant) in complex with ADP
5X0G: “Free serine kinase (E30A mutant) in complex with ADP”. X-ray diffraction, 3 ligands (AMP, ADP, 7WF), 3 pockets (best druggability 0.67). MolNFT v1 #138960 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5X0G
- Type
- protein
- Length
- 239 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Free serine kinase
- UniProt
- Q5JD03
- Ligands
- AMP, ADP, 7WF
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Free serine kinase | protein | 239 | 35% helix, 28% strand | Q5JD03 |
Ligands and binding sites
- AMP · Adenosine monophosphate · ligand · chains A
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- 7WF · 2-hydroxy-3-[4-(2-hydroxy-3-sulfopropyl)piperazin-1-yl]propane-1-sulfonic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 518 | 0.67 | 0.77 | 58 | AMP, ADP |
| 2 | 119 | 0.57 | 0.84 | 27 | empty |
| 3 | 93 | 0.38 | 0.76 | 19 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5JD03
- Elsewhere: RCSB PDB 5X0G · PDBe 5X0G · UniProt Q5JD03
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.