MolNFT v1 · #138823 · protein

Crystal structure of a mutant insect group III chitinase complex with (GLCNAC)5 (CAD1-E647L-(GLCNAC)5 ) from ostrinia furnacalis

5WVG: “Crystal structure of a mutant insect group III chitinase complex with (GLCNAC)5 (CAD1-E647L-(GLCNAC)5 ) from…”. X-ray diffraction, 1 ligand (NAG), 3 pockets (best druggability 0.66). MolNFT v1 #138823 on GenesisL1: 3D structure…

PDB: 5WVG
Type: protein
Length: 370 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chitinase
EC: 3.2.1.14
UniProt: U5LUV7
Ligands: NAG
Pockets: 3 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chitinase (EC 3.2.1.14)	protein	370	37% helix, 23% strand	U5LUV7

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 6 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	411	0.66	0.78	50	NAG
2	85	0.43	0.80	20	empty
3	59	0.35	0.78	15	empty

Modifications

Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

5WVG · Crystal structure of a mutant insect group III chitinase complex with (GlcNAc)5… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt U5LUV7
Elsewhere: RCSB PDB 5WVG · PDBe 5WVG · UniProt U5LUV7

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